Type B brain natriuretic peptide (proBNP) is a precursor to the heart to make up this contraction and inability to increase, the XinBi stretch by heart release it into the blood when the chemicals. ProBNP release level and myocardial burden level have direct correlation. Once from the heart to the release of the breakfast into the bloodstream, proBNP will be divided into NT-proBNP and BNP. BNP is a kind of biological activity of protein, and BNP instead, NT-proBNP biology is not active, this means that NT-proBNP can trace a longer time remains the same, but the long time tracking, using simple and efficient. Because the half failure NT-proBNP period for 60 to 120 minutes, can track time up to 24 hours, in contrast, the half-life of BNP is 20 minutes, the maximum of the monitoring time only 1 hour. Because long half-life, so NT-proBNP detection provides higher sensitivity to clinical doctors can accurately found early and mild heart failure. In addition, the BNP levels but also by the choice of medical intervention effects, such as using the nesiritide (based on the BNP to cure) for patients with treatment; The treatment can cause blood BNP levels.
In this case, clinical doctors may not be through the test of the BNP levels to distinguish BNP increase is caused by drug treatment, or cardiac function obstacle is the result of. But through the detection of patients with in the blood of the NT-proBNP concentration level, clinical doctors about the possibility of heart failure can be and how severe the important information for the collection, can even without any symptoms of patients for monitoring.
NT-proBNP in vitro diagnostic reagents application value
NT-proBNP by U.S. FDA approval for strength; diagnosis and evaluation, and patients with acute coronary syndrome of risk assessment; There is also evidence that NT-proBNP in the evaluation of the increased risk of cardiovascular events and stable coronary artery disease mortality in patients with prognostic value.
Perlong medical, nanjing branch biological technology Co., LTD. Is professional production clinical reagent, myocardial product brand company, major is born in NT-proBNP have a wide range of spread the use of it. And the user response excellent results
Below introduce you to the production of medical perlong NT-proBNP part of the information.
The NT-proBNP diagnostic kit for the add three experts crystallization of the wisdom of seven years, leading technology double double control, and increase detecting window wide, and to improve the diagnostic value minimum detection limit than 100 pg/ml, sensitivity for Chinese technical design, qualitative and quantitative double judgment, diagnosis more flexible detection speed, 10 to 20 minutes issued by rapid results, storage, convenient, 4 ~ 30 ℃ preservation. The test method:
1, before the tests first, please read the instructions complete, before the use will test card and sample return to room temperature (temperature suggested 20 ~ 25 ℃ in) and Numbers.
2, take out the test card from bags, should be in 1 hour to use as soon as possible.
3, will test card in the level of the place clean mesa, level and make markers placed.
4, with the move from 120 < mu > l liquid sample, or with products take small straw drain sample, vertical drop add 3 ~ 4 drops to add in the sample.
5, waiting for T line is in red strip appear, with visual reference standard for half quantitative interpretation than color card or will test card placed in the FIA8000 immune quantitative analyzer series, the quantitative detection, test results shall be in 10 to 30 minutes to read, to control the line at the end of the following the exhibition white advisable, 30 minutes to read the results don't reliable.
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